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Patients face risky choices after insurance denials for popular new weight-loss drugs

by Celia

In November 2021, Macarena Khoury embarked on a transformative journey with the weight loss medication Wegovy, with a starting BMI of 37 and constant thoughts about food dominating her daily life. Running her own interior design business, Khoury, 37, originally from Chile, had experienced significant weight gain due to changes in diet and multiple pregnancies. Wegovy, however, proved to be a game-changer for her, alleviating the incessant mental chatter about food and helping her shed 80 pounds in just 10 months.

Despite her success, Khoury faced an unexpected setback when her husband’s job change led to a switch in insurance, leaving Wegovy’s hefty monthly cost of over $1,300 without coverage. Forced to discontinue the medication, Khoury experienced a 40-pound weight regain and a resurgence of intense hunger.

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Unfortunately, Khoury’s situation is not unique. Many individuals find themselves in similar predicaments, having achieved success with powerful weight loss drugs only to lose access due to insurance limitations. The issue stems from the fact that most employer insurance plans and Medicare do not cover popular GLP-1 medications like Wegovy, creating financial barriers for individuals seeking effective weight loss solutions.

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A survey conducted in October 2023 revealed that only about 1 in 4 employers covered GLP-1 drugs for weight loss, and even though 43% are considering offering them, some are narrowing eligibility criteria to control costs. This includes utilization management and the requirement to try alternative therapies before qualifying for GLP-1 drugs.

Dr. Dan Azagury, medical director of the Stanford Bariatric and Metabolic Interdisciplinary Clinic, highlighted the common practice of insurance companies creating hurdles for patients, such as trying less effective and potentially side-effect-ridden medications before approving coverage for more expensive options. This approach, he argues, is shortsighted and counterproductive, as studies indicate that most patients regain weight after discontinuing GLP-1 drugs.

Economists argue that while the medications are expensive, potential long-term cost savings could outweigh the initial investment by preventing serious conditions like heart disease and diabetes. However, insurers remain hesitant, citing uncertainties about the long-term effects of these drugs and a misalignment of incentives, as patients may shift their healthcare costs to Medicare after retirement.

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The restrictive insurance landscape has led to increasing frustration among healthcare practitioners. Dr. Kimberly Gudzune, the medical director for the American Board of Obesity Medicine, expressed concern about the reactionary and changing requirements for maintaining coverage, creating challenges for both healthcare providers and patients.

For individuals like Khoury, alternatives, such as sourcing medications from Canada or resorting to compounding pharmacies for custom-made versions of approved drugs, come with their own set of risks and uncertainties. While Khoury’s out-of-pocket costs rose significantly, she remains hopeful that one day access to these life-changing medications won’t be a financial burden.

The ongoing struggles faced by individuals like Macarena Khoury shed light on the complex interplay between insurance coverage, drug accessibility, and the long-term well-being of those seeking effective weight loss solutions. As the conversation surrounding the coverage of GLP-1 medications continues, the broader implications for public health and cost savings remain at the forefront of this ongoing debate.

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